In a multi team development environment, changes can be made to an integration such as ingesting a new field in a dev environment (ie adding a new attribute to an entity). Using Integration Builder, this attribute might be added to the integration and work as expected in the Development environment.
However, if that integration is now required to be deployed with those changes through to production, but the integrated database doesn't have the required attribute deployed to production, this can cause production errors.
My suggestion is to provide a log of changes showing what additions or subtractions have been made to an integration so that they can be validated prior to any deployment. Alternatively, during the preparation of a deployment, test that all integration attributes are valid and pause a deployment to alert of this missing attribute.